diff --git a/driver/cl_options_sanitizers.cpp b/driver/cl_options_sanitizers.cpp
index 2299cd48ca..92ffea5738 100644
--- a/driver/cl_options_sanitizers.cpp
+++ b/driver/cl_options_sanitizers.cpp
@@ -15,8 +15,10 @@
 #include "driver/cl_options_sanitizers.h"
 
 #include "ddmd/errors.h"
+#include "ddmd/dsymbol.h"
 #include "llvm/ADT/StringSwitch.h"
 #include "llvm/Support/raw_ostream.h"
+#include "llvm/Support/SpecialCaseList.h"
 
 namespace {
 
@@ -28,6 +30,13 @@ cl::list<std::string> fSanitize(
              "suspicious behavior."),
     cl::value_desc("checks"));
 
+cl::list<std::string> fSanitizeBlacklist(
+    "fsanitize-blacklist", cl::CommaSeparated,
+    cl::desc("Add <file> to the blacklist files for the sanitizers."),
+    cl::value_desc("file"));
+
+std::unique_ptr<llvm::SpecialCaseList> sanitizerBlacklist;
+
 #ifdef ENABLE_COVERAGE_SANITIZER
 cl::list<std::string> fSanitizeCoverage(
     "fsanitize-coverage", cl::CommaSeparated,
@@ -149,6 +158,14 @@ void initializeSanitizerOptionsFromCmdline()
     sancovOpts.CoverageType = llvm::SanitizerCoverageOptions::SCK_Edge;
   }
 #endif
+
+  if (isAnySanitizerEnabled() && !fSanitizeBlacklist.empty()) {
+    std::string loadError;
+    sanitizerBlacklist =
+        llvm::SpecialCaseList::create(fSanitizeBlacklist, loadError);
+    if (!sanitizerBlacklist)
+      error(Loc(), "-fsanitize-blacklist error: %s", loadError.c_str());
+  }
 }
 
 #ifdef ENABLE_COVERAGE_SANITIZER
@@ -180,4 +197,9 @@ void outputSanitizerSettings(llvm::raw_ostream &hash_os) {
 #endif
 }
 
+bool functionIsInSanitizerBlacklist(FuncDeclaration *funcDecl) {
+  return sanitizerBlacklist &&
+         sanitizerBlacklist->inSection("fun", mangleExact(funcDecl));
+}
+
 } // namespace opts
diff --git a/driver/cl_options_sanitizers.h b/driver/cl_options_sanitizers.h
index d99b8aac08..56d043c914 100644
--- a/driver/cl_options_sanitizers.h
+++ b/driver/cl_options_sanitizers.h
@@ -23,6 +23,7 @@
 #define ENABLE_COVERAGE_SANITIZER
 #endif
 
+class FuncDeclaration;
 namespace llvm {
 class raw_ostream;
 }
@@ -54,6 +55,8 @@ llvm::SanitizerCoverageOptions getSanitizerCoverageOptions();
 
 void outputSanitizerSettings(llvm::raw_ostream &hash_os);
 
+bool functionIsInSanitizerBlacklist(FuncDeclaration *funcDecl);
+
 } // namespace opts
 
 #endif // LDC_DRIVER_CL_OPTIONS_SANITIZERS_H
diff --git a/gen/functions.cpp b/gen/functions.cpp
index 9bc5e53623..be7abf2cca 100644
--- a/gen/functions.cpp
+++ b/gen/functions.cpp
@@ -954,7 +954,8 @@ void DtoDefineFunction(FuncDeclaration *fd, bool linkageAvailableExternally) {
   if (gABI->needsUnwindTables()) {
     func->addFnAttr(LLAttribute::UWTable);
   }
-  if (opts::isAnySanitizerEnabled()) {
+  if (opts::isAnySanitizerEnabled() &&
+      !opts::functionIsInSanitizerBlacklist(fd)) {
     // Set the required sanitizer attribute.
     if (opts::isSanitizerEnabled(opts::AddressSanitizer)) {
       func->addFnAttr(LLAttribute::SanitizeAddress);
diff --git a/tests/sanitizers/fsanitize_blacklist.d b/tests/sanitizers/fsanitize_blacklist.d
new file mode 100644
index 0000000000..816f2bf8e5
--- /dev/null
+++ b/tests/sanitizers/fsanitize_blacklist.d
@@ -0,0 +1,63 @@
+// Test sanitizer blacklist functionality
+
+// RUN: %ldc -c -output-ll -fsanitize=address \
+// RUN: -fsanitize-blacklist=%S/inputs/fsanitize_blacklist.txt \
+// RUN: -fsanitize-blacklist=%S/inputs/fsanitize_blacklist2.txt \
+// RUN: -of=%t.ll %s && FileCheck %s < %t.ll
+
+// Don't attempt to load the blacklist when no sanitizer is active
+// RUN: %ldc -o- -fsanitize-blacklist=%S/thisfilecertainlydoesnotexist %s
+
+// CHECK-LABEL: define {{.*}}9foofoofoo
+// CHECK-SAME: #[[ATTR_WITHASAN:[0-9]+]]
+void foofoofoo(int* i)
+{
+    // CHECK: call {{.*}}_asan
+    *i = 1;
+}
+
+// CHECK-LABEL: define {{.*}}blacklisted
+// CHECK-SAME: #[[ATTR_NOASAN:[0-9]+]]
+extern (C) void blacklisted(int* i)
+{
+    // CHECK-NOT: call {{.*}}_asan
+    *i = 1;
+}
+
+// Test blacklisted wildcard
+// CHECK-LABEL: define {{.*}}10black_set1
+// CHECK-SAME: #[[ATTR_NOASAN:[0-9]+]]
+void black_set1(int* i)
+{
+    // CHECK-NOT: call {{.*}}_asan
+    *i = 1;
+}
+// CHECK-LABEL: define {{.*}}10black_set2
+// CHECK-SAME: #[[ATTR_NOASAN:[0-9]+]]
+void black_set2(int* i)
+{
+    // CHECK-NOT: call {{.*}}_asan
+    *i = 1;
+}
+
+//  Test blacklisting of template class methods
+class ABCDEF(T)
+{
+    void method(int* i)
+    {
+        *i = 1;
+    }
+}
+
+// CHECK-LABEL: define {{.*}}TiZ6ABCDEF6method
+// CHECK-SAME: #[[ATTR_NOASAN:[0-9]+]]
+ABCDEF!int ofBlacklistedType;
+
+// CHECK-LABEL: define {{.*}}TAyaZ6ABCDEF6method
+// CHECK-SAME: #[[ATTR_WITHASAN:[0-9]+]]
+ABCDEF!string ofInstrumentedType;
+
+//CHECK: attributes #[[ATTR_WITHASAN]] ={{.*}}sanitize_address
+//CHECK: attributes #[[ATTR_NOASAN]]
+//CHECK-NOT: sanitize_address
+//CHECK-SAME: }
diff --git a/tests/sanitizers/inputs/fsanitize_blacklist.txt b/tests/sanitizers/inputs/fsanitize_blacklist.txt
new file mode 100644
index 0000000000..e4af0719bf
--- /dev/null
+++ b/tests/sanitizers/inputs/fsanitize_blacklist.txt
@@ -0,0 +1,13 @@
+# Blacklist for the sanitizers. Turns off instrumentation of particular
+# functions or sources. Use with care. You may set location of blacklist
+# at compile-time using -fsanitize-blacklist=<path> flag.
+
+# Example usage:
+# fun:*bad_function_name*
+# src:file_with_tricky_code.cc
+# global:*global_with_bad_access_or_initialization*
+# global:*global_with_initialization_issues*=init
+# type:*Namespace::ClassName*=init
+
+fun:blacklisted
+fun:*black_set*
diff --git a/tests/sanitizers/inputs/fsanitize_blacklist2.txt b/tests/sanitizers/inputs/fsanitize_blacklist2.txt
new file mode 100644
index 0000000000..3a0b098694
--- /dev/null
+++ b/tests/sanitizers/inputs/fsanitize_blacklist2.txt
@@ -0,0 +1 @@
+fun:_D*TiZ6ABCDEF6method*